Molecular basis of antibiotic permeability in Gram-negative bacteria

Solving a new question within a private-public partnership

June 21st – 23rd, 2017
Helmholtz Centre for Infection Research, Braunschweig, Germany

Abstracts | Pictures

Wednesday, June 21st

Arrival day
Introduction – Chaired by NAME –
09:00 D. Heinz (Scientific Director of the Helmholtz Centre for Infection Research, Braunschweig, Germany)
09:15 R. Stavenger (GlaxoSmithKline, Collegeville, PA, USA)
09:45 H. Nikaido – keynote speaker (Professor of the Graduate School Division of Biochemistry, UC Berkeley, USA)
10:30 Coffee break
11:15 R. Hancock (Professor of the Graduate School Division of Biochemistry, Biophysics and Structural Biology, UC Berkeley, USA)
Search for new molecules and strategies – Chaired by NAME –
12:00 A. Edwards (Structural Genomics Consortium, UK)
12:30 P. Gribbon (Fraunhofer Hamburg, Germany)
13:00 Lunch
Whole cell assays – Chaired by NAME –
11:00 M. Brönstrup (Helmholtz Zentrum Braunschweig, Germany)
11:30 M. Masi (Aix-Marseille University, France)

Whole-cell-based Assay to Evaluate Permeation of ß-Lactam Antibiotics through OmpF/C porin orthologs

12:00 M. Mourez (Sanofi-Aventis Lyon, France)
15:30 Coffee break
16:00 M. Refrigiers & E. Dumont (Synchrotron Soleil, Paris, France)

Microspectrofluorimetry dissection of the antibiotic accumulation in Gram-negative bacteria

Porin Pathway– Chaired by NAME –
16:30 B. van den Berg (University of Newcastle, UK)
17:00 W. Im (Lehigh University, USA)
17:30 U. Kleinekathöfer (Jacobs University Bremen, Germany)
19:00 Poster session


Thursday, June 22nd

Uptake systems – Chaired by NAME –
09:00 TBA
09:30 T. Köhler (Université de Geneve-Hopital, Switzerland)
10:00 J. Naismith  (University of St. Andrews, UK)
10:30 Coffee break
11:00 I. Schalk  (University of Strasbourg, France)
11:30 M. Ceccarelli (University of Cagliari, Italy)
12:00 H. Schweizer (University Florida, USA)
12:30 TBA
13:00 Lunch
Cell Wall – Chaired by NAME –
14:00 D. Bumann (Biozentrum Basel, Swizerland)
14:30 H. Brötz-Österhelt (Eberhard Karls Universität Tübingen, Germany)
15:00 M. Page (Jacobs University Bremen, Germany)
15:30 Coffee break
16:00 TBA
16:30 TBA
17:00 TBA
17:30 TBA
19:00 Poster session

Round Table


Friday, June 23rd

Efflux systems – Chaired by NAME –
09:00 L. Piddock (University of Birmingham, UK)
09:30 K. M. Pos (Universität Frankfurt, Germany)
10:00 P. Ruggerone (University of Cagliari, Italy)
10:30 Coffee break
11:00 M. Picard (CNRS Paris, France)
11:30 TBA
12:00 TBA
13:00 Lunch
14:00 B. Luisi (University of Cambridge, UK)
14:30 H. Zgurskaya (University of Oklahoma, USA)
10:00 O. Lomovskaya (The Medicines Company, USA)
15:30 Coffee break
Concluding remarks
16:00 M. Winterhalter (Jacobs University Bremen, Germany)